The CYCLOCALYX study: Ovulatory cycle affects circulating compartments of the endothelial glycocalyx in blood.
Nikolai HuldeNina RogenhoferFlorian BrettnerNicole C EckertIsabella GötzfriedThu NguyenJudith-I PagelTobias KammererKlaus F Hofmann-KieferGustav SchellingAndreas DendorferMarkus RehmChristian J ThalerPublished in: American journal of reproductive immunology (New York, N.Y. : 1989) (2017)
The relationship between the natural menstrual cycle and the EGX as an indicator of vascular permeability may provide a new explanation for premenstrual edema in healthy women. This may be an attendant phenomenon of a regular physiological process, the hormonal downregulation of the vascular barrier during pregnancy.