Tumor-derived exosomes in the regulation of macrophage polarization.
Mubashir Baig MirzaAnjali RoySajjan RajpootDongfang LiuRajkumar SavaiSreeparna BanerjeeManabu KawadaSyed M FaisalRohit SalujaUzma SaqibTomokazu OhishiKishore K WaryPublished in: Inflammation research : official journal of the European Histamine Research Society ... [et al.] (2020)
Based on the vesicular cargo, the molecular constituents, the exosomes have the potential to change the fate of macrophage phenotypes, either M1, classically activated macrophages, or M2, alternatively activated macrophages. In this review, we discuss and describe the ability of tumor-derived exosomes in the mechanism of macrophage activation and polarization.