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Molecular and genomic typing for tuberculosis surveillance: A survey study in 26 European countries.

Marta AndrésMarieke J van der WerfCsaba KödmönStefan AlbrechtWalter HaasLena Fiebignull null
Published in: PloS one (2019)
Our study shows a wide use of molecular and genomic typing data for TB surveillance in EU/EEA countries and reveals that transition to WGS-based typing is ongoing or is considered in most countries. However, our results also show a high heterogeneity in the use and integration of typing data for TB surveillance. Standardization of typing data use for TB surveillance is needed and formal procedures should be developed to facilitate international collaboration.
Keyphrases
  • mycobacterium tuberculosis
  • public health
  • electronic health record
  • genetic diversity
  • big data
  • copy number
  • machine learning
  • single cell
  • single molecule
  • data analysis
  • dna methylation