New clinical data on human spinal cord re-irradiation tolerance.
Hiroshi DoiKeisuke TamariRyoong-Jin OhCarsten NiederPublished in: Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] (2021)
Even patients treated to higher cumulative doses than previously recommended, or at a considerable risk of myelopathy according to a published risk score, remained free from this complication, although one must acknowledge the potential for manifestation of damage in patients currently alive, i.e., still at risk. Individualized decisions to re-irradiate after appropriate informed consent are an acceptable strategy, including scenarios where low re-irradiation doses to the spinal cord would compromise target coverage and tumor control probability to an unacceptable degree.
Keyphrases
- spinal cord
- end stage renal disease
- spinal cord injury
- neuropathic pain
- newly diagnosed
- ejection fraction
- endothelial cells
- peritoneal dialysis
- climate change
- healthcare
- prognostic factors
- systematic review
- radiation induced
- big data
- machine learning
- electronic health record
- risk assessment
- patient reported outcomes
- health insurance
- data analysis