Effects of intrathecal pemetrexed on the survival of patients with leptomeningeal metastasis from lung adenocarcinoma: a propensity score matching analysis.
Yaping HongQian MiaoXinlong ZhengYiquan XuYunjian HuangShengjia ChenZhangzhou HuangHaipeng XuKan JiangQiaofeng ZhongLongfeng ZhangXiaobin ZhengHongfu ZengShanshan YangYujing LiShihui LiWu ZhuangGen LinPublished in: Journal of neuro-oncology (2023)
Intrathecal pemetrexed did not enhance OS for the entire LUAC patient with LM compared to non-intrathecal chemotherapy. However, it exhibited the potential to reduce the risk of central nervous system-related mortality and improve survival in patients with poor ECOG PS.