Adiponectin Isoform Patterns in Ethnic-Specific ADIPOQ Mutation Carriers: The IRAS Family Study.
Keri L TabbChuan GaoPamela J HicksGregory A HawkinsJerome I RotterYii-Der Ida ChenXiuqing GuoJill M NorrisCarlos LorenzoBarry I FreedmanDonald W BowdenNicholette D D AllredPublished in: Obesity (Silver Spring, Md.) (2017)
The results contrast with the proposed biological importance of the HMW multimer. This suggests that the LMW isoform may functionally compensate for some of the loss or reduction of the higher-order multimers in carriers of the G45R and R55C mutations.