Network Pharmacology Study on Molecular Mechanisms of Zhishi Xiebai Guizhi Decoction in the Treatment of Coronary Heart Disease.

Jin Gao Yujing Pan Yuxi Zhao Haoyang Li Zishuo Mi Hao Chen Xiaodong Tan

Published in: Evidence-based complementary and alternative medicine : eCAM (2021)

. TNF signaling pathway, AMPK signaling pathway, and PI3K-Akt signaling pathway are potential mechanisms as well. The application of network pharmacology can provide a novel method for the research of Chinese herbal medicine. We hope that Zhishi Xiebai Guizhi Decoction will be recognized as a complementary or alternative treatment for coronary heart disease.

Keyphrases

signaling pathway
pi k akt
cell cycle arrest
cell proliferation
epithelial mesenchymal transition
induced apoptosis
oxidative stress
climate change