Background: Despite rising rates of obesity among human immunodeficiency virus (HIV)-positive individuals, the safety and tolerability of surgery in this population have not been established. The primary aim of this study was to examine the safety of bariatric surgery and rate of in-hospital postoperative complications in morbidly obese patients with HIV. Materials and Methods: The U.S. Nationwide Inpatient Sample database was queried between 2004 and 2014 for discharges with codiagnoses of morbid obesity and bariatric surgery. The primary outcome was in-hospital mortality. Secondary outcomes included length of stay, hospitalization costs, and multiple categories of complications, including systemic complications, surgical complications, and nutritional and behavioral complications. Results: Among 267,082 patients with discharge diagnoses of morbid obesity and bariatric surgery, 346 (0.13%) were diagnosed with HIV. On multivariable analysis, HIV did not influence in-hospital mortality (p = 0.530). HIV was not associated with increased risk of renal failure (p = 0.274), thromboembolism (p = 0.713), myocardial infarction (p = 0.635), sepsis (p = 0.757), hemorrhage (p = 0.303), or wound infection (p = 0.229). Other measured surgical complications were not significantly different (p > 0.05). Notably, HIV-positive patients had an increased risk for postoperative pneumonia (p = 0.002), pancreatitis (p = 0.049), and thiamine deficiency (p = 0.016). Conclusion: Bariatric surgery among HIV-positive patients appears to be acceptably safe with the risk of postoperative complications comparable with non-HIV patients.
Keyphrases
- hiv positive
- bariatric surgery
- antiretroviral therapy
- human immunodeficiency virus
- weight loss
- men who have sex with men
- obese patients
- hiv infected
- south africa
- hepatitis c virus
- hiv aids
- hiv testing
- end stage renal disease
- metabolic syndrome
- type diabetes
- peritoneal dialysis
- ejection fraction
- newly diagnosed
- risk factors
- insulin resistance
- healthcare
- prognostic factors
- adipose tissue
- chronic kidney disease
- heart failure
- skeletal muscle
- weight gain
- body mass index
- palliative care
- intensive care unit
- patients undergoing
- patient reported
- surgical site infection