Single-centre prospective evaluation of the first 5 years of cystic fibrosis newborn screening in Germany.

Florian GesenhuesKatarzyna MichelTobias GreveWulf RöschingerFlorian GotheJenna NüblingMaria FeilckeCarolin KrönerIngo PawlitaFranziska SattlerElias SeidlMatthias GrieseMatthias Kappler

Published in: ERJ open research (2024)

by extending the DNA analysis within the screening algorithm and by increasing the number of variants tested. The Bavarian tracking system can serve as a successful model for other tracking systems. We preferred the Macroduct system because of its more accurate sweat conductivity readings.

Keyphrases

cystic fibrosis
machine learning
pseudomonas aeruginosa
copy number
deep learning
high resolution
lung function
chronic obstructive pulmonary disease
dna methylation
nucleic acid