High flow nasal oxygen versus conventional oxygen therapy in gastrointestinal endoscopy with conscious sedation: Systematic review and meta-analysis with trial sequential analysis.

Wan-Jie GuHao-Tian WangJiao HuangJun-Peng PeiKazuhiro NishiyamaMasanobu AbeZhe-Ming ZhaoChun-Dong Zhang

Published in: Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society (2022)

Compared with COT, HFNO can reduce the risk of hypoxemia and improve the lowest oxygen saturation in gastrointestinal endoscopy with conscious sedation. However, the results should be interpreted with caution due to substantial heterogeneity and limited evidence. Further studies are needed to verify the preliminary findings.

Keyphrases

small bowel
mechanical ventilation
clinical trial
study protocol
single cell
phase ii
intensive care unit
bone marrow
replacement therapy