Severe enterovirus infections in patients with immune-mediated inflammatory diseases receiving anti-CD20 monoclonal antibodies.
Gregoire Martin de FremontHélène ChabrollesAudrey MirandAnne Sophie L'HonneurNicolas MéléBertrand DunogueDavid BoutboulMeryem FarhatEric HachullaMouna LazrekVirginie RieuAlexis MathianHelene ChaussadeAurelie RuetSonia BurrelFabienne CouryIsabelle SchuffeneckerAdrien LemaignenKarl SteficMaelle le BesneraisMarion CarretteLuc MouthonVeronique Avettand-FenoelBenjamin TerrierJérome HadjadjPublished in: RMD open (2024)
EV infection should be evoked in patients with IMIDs presenting with atypical organ involvement, especially meningoencephalitis. Anti-CD20 mAbs may lead to impaired B-cell response against EV, although an underlying primary immunodeficiency should systematically be discussed.