Serum protein binding of 25 antiepileptic drugs in a routine clinical setting: A comparison of free non-protein-bound concentrations.

Philip N PatsalosMiguel ZugmanCharlotte LakeAnthony JamesNeville RatnarajJosemir W Sander

Published in: Epilepsia (2017)

These data provide a comprehensive comparison of serum protein binding of all available AEDs including the metabolites, carbamazepine-epoxide and N-desmethyl-clobazam. Knowledge of the free fraction of these AEDs can be used to optimize epilepsy treatment.

Keyphrases

binding protein
protein protein
amino acid
healthcare
electronic health record
machine learning
dna binding
small molecule
clinical practice
transcription factor
replacement therapy
data analysis