Serum protein binding of 25 antiepileptic drugs in a routine clinical setting: A comparison of free non-protein-bound concentrations.
Philip N PatsalosMiguel ZugmanCharlotte LakeAnthony JamesNeville RatnarajJosemir W SanderPublished in: Epilepsia (2017)
These data provide a comprehensive comparison of serum protein binding of all available AEDs including the metabolites, carbamazepine-epoxide and N-desmethyl-clobazam. Knowledge of the free fraction of these AEDs can be used to optimize epilepsy treatment.