A novel hybrid polymer of PCL/fish gelatin nanofibrous scaffold improves proliferation and differentiation of Wharton's jelly-derived mesenchymal cells into islet-like cells.

Seyedeh Masoumeh MirtaghiHadi HassanniaMohammadreza MahdaviZahra Hosseini-KhahAmir MellatiSeyed Ehsan Enderami

Published in: Artificial organs (2022)

Our findings showed the use of PCL/Fish gelatin nanofibrous scaffolds with optimized differentiation protocols can promote the differentiation of IPCs from WJ-MSCs compared to the 2D culture group.

Keyphrases

tissue engineering
induced apoptosis
stem cells
mesenchymal stem cells
umbilical cord
signaling pathway
bone marrow
endoplasmic reticulum stress
cell proliferation