Concomitant benzodiazepine and opioids decrease sleep apnoea risk in chronic pain patients.

Soodaba MirJean WongClodagh M RyanGeoff BellinghamMandeep SinghRida WaseemDanny J EckertFrances Chung

Published in: ERJ open research (2020)

In chronic pain patients on opioids, administration of certain benzodiazepine sedatives induced a mild respiratory depression but paradoxically reduced sleep apnoea risk and severity by increasing the respiratory arousal threshold.

Keyphrases

chronic pain
end stage renal disease
pain management
ejection fraction
newly diagnosed
peritoneal dialysis
physical activity
sleep quality
depressive symptoms
obstructive sleep apnea
positive airway pressure