Preventive effects of early immunosuppressive treatment on the development of interstitial lung disease in systemic sclerosis.
Arthiha VelauthapillaiM F R BootsmaCosimo BruniChristina BergmannMarco Matucci CerinicDavid LaunayGabriela RiemekastenLiudmila GarzanovaPaolo AiróElena RezușJosé António Pereira Da SilvaFrancesco Del GaldoN HunzelmannLorinda S ChungDorota Maria KrasowskaOliver DistlerCornelia H M van den EndeMadelon C Vonknull nullPublished in: Rheumatology (Oxford, England) (2024)
Our findings did not confirm a preventive role of early initiation of immunosuppressive therapy vs late initiation on ILD development. However, our findings should be interpreted with caution, considering the high inflammatory, ATA-positive enriched nature of the cohort, confounding by indication, and very few patients were treated with biologicals.