Clinical and Immunological Heterogeneity in Japanese Patients with Gain-of-Function Variants in STAT3.

Kay TanitaFumiaki SakuraRyusuke NambuMiyuki TsumuraYusuke ImanakaHidenori OhnishiZenichiro KatoJie PanAkihiro HoshinoKoji SuzukiMotoko YasutomiShuichiro UmetsuChizuru OkadaMasatoshi TakagiKohsuke ImaiOsamu OharaAlexo M MuiseSatoshi OkadaTomohiro MorioHirokazu Kanegane

Published in: Journal of clinical immunology (2021)

Patients with STAT3 GOF variants exhibited clinical and immunological heterogeneity with incomplete penetrance.

Keyphrases

copy number
single cell
cell proliferation
gene expression
dna methylation