Optimized detection of germ cell neoplasia in situ in contralateral biopsy reduces the risk of second testis cancer.
Ewa Rajpert-De MeytsNiels JørgensenJørgen Holm PetersenKristian AlmstrupLise AksglaedeJakob LauritsenMikael RørthGedske DaugaardNiels E SkakkebaekPublished in: BJU international (2022)
Optimized diagnostic procedures improved the detection rate of GCNIS in patients with TGCT and minimized their risk of developing metachronous bilateral cancer. Urologists should be aware of the importance of careful tissue excision (to avoid mechanical compression) and the need of adequate biopsy size. Performing contralateral biopsies is beneficial for patients' care and should be offered as a part of their management.
Keyphrases
- germ cell
- papillary thyroid
- end stage renal disease
- ultrasound guided
- squamous cell
- healthcare
- newly diagnosed
- ejection fraction
- chronic kidney disease
- loop mediated isothermal amplification
- palliative care
- prognostic factors
- peritoneal dialysis
- fine needle aspiration
- real time pcr
- high grade
- quality improvement
- childhood cancer
- patient reported
- young adults
- liver metastases