Artesunate shows potent anti-tumor activity in B-cell lymphoma.

Thea Kristin VåtsveenMarit Renée MyhreChloé Beate SteenSébastien WälchliOle Christian LingjærdeBaoyan BaiPierre DillardTheodossis A TheodossiouToril HolienAnders SundanElse Marit InderbergErlend B SmelandJune Helen MyklebustMorten P Oksvold

Published in: Journal of hematology & oncology (2018)

Artesunate demonstrated potent apoptosis-inducing effects across a broad range of B-cell lymphoma cell lines in vitro, and a prominent anti-lymphoma activity in vivo, suggesting it to be a relevant drug for treatment of B-cell lymphoma.

Keyphrases

diffuse large b cell lymphoma
oxidative stress
endoplasmic reticulum stress
cell cycle arrest
combination therapy
smoking cessation