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Type I pig collagen enhances the efficacy of PEDF 34-mer peptide in a mouse model of laser-induced choroidal neovascularization.

Hyun Woong KimKug-Hwan RohSeong Wook KimSung Jae ParkNa-Young LimHana JungIl-Whan ChoiSae Gwang Park
Published in: Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie (2019)
Collagen can serve as a carrier and reservoir of PEDF34. PEDF peptide/collagen mixture is easy to prepare than conventional methods for maintaining the therapeutic effect of PEDF peptide.
Keyphrases
  • mouse model
  • wound healing
  • tissue engineering
  • optical coherence tomography
  • diabetic retinopathy
  • vascular endothelial growth factor