The efficacy and safety of acid suppressants for gastrointestinal bleeding prophylaxis in cardiac care unit patients.
Chen ChenHui LiuRuqiao DuanFangfang WangLi Ping DuanPublished in: Journal of gastroenterology and hepatology (2021)
Proton pump inhibitors and H2RAs for GIB prophylaxis in CCU patients were not associated with a lower risk of CIGIB than the controls. PPI therapy is associated with increased risks of HAP and in-hospital mortality in patients over 75 years old. PPIs may increase the risk of HAP in patients with heart failure.