Increased aortic stiffness and elevated blood pressure in response to exercise in adult survivors of prematurity.
Christopher R BarnardMatthew PetersAmy L SindlerEmily T FarrellKim R BakerMari PaltaHarald M StaussJohn M DagleJeffrey SegarGary L PierceMarlowe W EldridgeMelissa L BatesPublished in: Physiological reports (2021)
In this first report of the blood pressure response to exercise in adults born prematurely, we found exercise-induced hypertension relative to a term-born control group that is associated with increased large artery stiffness. These experiments performed in hypoxia reveal abnormalities in vascular function in adult survivors of prematurity that may further deteriorate as this population ages.
Keyphrases
- blood pressure
- low birth weight
- preterm infants
- gestational age
- high intensity
- hypertensive patients
- heart rate
- young adults
- preterm birth
- physical activity
- childhood cancer
- aortic valve
- genome wide
- left ventricular
- blood glucose
- pulmonary artery
- single cell
- gene expression
- skeletal muscle
- metabolic syndrome
- pulmonary arterial hypertension
- coronary artery
- weight loss