Combined Dextran-Graft-Polyacrylamide/Zinc Oxide Nanocarrier for Effective Anticancer Therapy in vitro.
Vasyl ChumachenkoPavlo A VirychGuochao NiePetro VirychOleg YeshchenkoPavlo S KhortAnton TkachenkoVolodymyr ProkopiukNataliia LukianovaTaras ZadvornyiMichel RawisoLiyao DingNataliya KutsevolPublished in: International journal of nanomedicine (2023)
The nanosystems were low-toxic to fibroblasts, MAEC. The D-PAA/ZnO NPs nanosystem synthesized using zinc sulphate demonstrates high cytotoxicity due to destruction of various types of cancer cells in vitro and potentially increases adhesion between cells. Thus, our findings indicate the selective cytotoxicity of D-PAA/ZnO NPs against cancer cells and can be potentially used for cancer treatment.