Mass Spectrometric and Artificial Intelligence-Based Identification of the Secretome of Plasmodium falciparum Merozoites to Provide Novel Candidates for Vaccine Development Pipeline.

Akshay MunjalDevasahayam Arokia Balaya RexPrachi GargThottethodi Subrahmanya Keshava PrasadSai Kumar MishraYuktika MalhotraDeepika YadavJerry JohnPreeti PKamal RawalShailja Singh

Published in: Proteomics. Clinical applications (2024)

We, for the first time, report the secretory repertoire of merozoite and its status for vaccine candidacy. This information can be utilized to develop better invasion blocking multisubunit vaccines, comprising of immunological epitopes from several secreted invasins.

Keyphrases

plasmodium falciparum
artificial intelligence
machine learning
big data
deep learning
cell migration
health information
healthcare
data analysis