Completed genome and emergence scenario of the multidrug-resistant nosocomial pathogen Staphylococcus epidermidis ST215.
Therese KellgrenChinmay DwibediMicael WiderströmDavid SundellCaroline ÖhrmanAndreas SjödinCaroline ÖhrmanPatrik RydénAnders F JohanssonPublished in: BMC microbiology (2024)
This study features the extensive antibiotic resistance and virulence gene content in ST215 genomes. ST215 and ST2 lineages have similarly evolved, acquiring resistance and virulence through genomic recombination. The results highlight the threat of new multidrug-resistant S. epidermidis lineages emerging in healthcare settings.
Keyphrases
- biofilm formation
- multidrug resistant
- staphylococcus aureus
- pseudomonas aeruginosa
- acinetobacter baumannii
- healthcare
- candida albicans
- escherichia coli
- drug resistant
- klebsiella pneumoniae
- gram negative
- copy number
- genome wide
- antimicrobial resistance
- dna damage
- dna repair
- gene expression
- dna methylation
- health insurance