Examining the Development of Chronic Thromboembolic Pulmonary Hypertension at the Single-Cell Level.

Ran MiaoXingbei DongJuanni GongYidan LiXiaojuan GuoJianfeng WangQiang HuangYing WangJifeng Li Suqiao YangTuguang KuangMin LiuJun WanZhen-Guo ZhaiJiuchang ZhongYuan-Hua Yang

Published in: Hypertension (Dallas, Tex. : 1979) (2021)

This single-cell RNA sequencing analysis revealed the order of single cells along a developmental trajectory in CTEPH as well as close communication between different cell types in CTEPH pathogenesis.

Keyphrases

single cell
rna seq
pulmonary hypertension
high throughput
induced apoptosis
cell cycle arrest
pulmonary artery
pulmonary arterial hypertension
stem cells
mesenchymal stem cells
bone marrow