Physiological effects of high-flow nasal cannula therapy in preterm infants.

Zheyi LiewAlan C FentonSundeep HarigopalSaikiran GopalakajeMalcolm BrodlieChristopher J O'Brien

Published in: Archives of disease in childhood. Fetal and neonatal edition (2019)

HFNC therapy produces clinically significant pEEP with large variability at higher flow rates. Highest pressures were observed in infants weighing <1000 g. Flow, weight and mouth position are all important determinants of pressures generated. Reductions in pEECO2 support HFNC's role in dead space washout.

Keyphrases

preterm infants
body mass index
physical activity
extracorporeal membrane oxygenation
weight loss
stem cells
weight gain
intensive care unit
mesenchymal stem cells
respiratory failure
body weight
acute respiratory distress syndrome