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Adaptive behavior in autism: Minimal clinically important differences on the Vineland-II.

Christopher ChathamK I TaylorT CharmanX Liogier D'ardhuyE EuleA FedeleA Y HardanE LothL MurtaghMarta Del Valle RubidoA San Jose CaceresJ SevignyL SikichL SnyderJ E TillmannP E VentolaK L Walton-BowenP P WangT WillgossF Bolognani
Published in: Autism research : official journal of the International Society for Autism Research (2017)
The Vineland Adaptive Behavior Scales (2nd edition; Vineland-II) is the most widely used scale for assessing day-to-day "adaptive" skills. Yet, it is unknown how much Vineland-II scores must change for those changes to be regarded as clinically significant. We pooled data from over 9,000 individuals with ASD to show that changes of 2-3.75 points on the Vineland-II Composite score represent the "minimal clinically-important difference." These estimates will help evaluate the benefits of potential new treatments for ASD.
Keyphrases
  • autism spectrum disorder
  • intellectual disability
  • attention deficit hyperactivity disorder
  • electronic health record
  • machine learning
  • artificial intelligence