Adaptive behavior in autism: Minimal clinically important differences on the Vineland-II.
Christopher ChathamK I TaylorT CharmanX Liogier D'ardhuyE EuleA FedeleA Y HardanE LothL MurtaghMarta Del Valle RubidoA San Jose CaceresJ SevignyL SikichL SnyderJ E TillmannP E VentolaK L Walton-BowenP P WangT WillgossF BolognaniPublished in: Autism research : official journal of the International Society for Autism Research (2017)
The Vineland Adaptive Behavior Scales (2nd edition; Vineland-II) is the most widely used scale for assessing day-to-day "adaptive" skills. Yet, it is unknown how much Vineland-II scores must change for those changes to be regarded as clinically significant. We pooled data from over 9,000 individuals with ASD to show that changes of 2-3.75 points on the Vineland-II Composite score represent the "minimal clinically-important difference." These estimates will help evaluate the benefits of potential new treatments for ASD.