Gastro-Intestinal Digested Bovine Milk Osteopontin Modulates Gut Barrier Biomarkers In Vitro.

Lu LiJuchun ChenYuxing ZhengJonathan LaneRuibiao HuJianzhong ZhuXiong FuQiang HuangFeitong LiuBin Zhang

Published in: Molecular nutrition & food research (2024)

The findings demonstrate that the bioactive peptides released from in vitro infant gastrointestinal digestion of bovine milk OPN alleviates intestinal epithelial cell inflammation by inhibiting NF-κB pathway activation and potentiates the barrier function of the intestinal epithelium.

Keyphrases

signaling pathway
oxidative stress
mouse model
nuclear factor
risk assessment
amino acid
inflammatory response
tissue engineering