Microsatellite Instability in Patients With Stage III Colon Cancer Receiving Fluoropyrimidine With or Without Oxaliplatin: An ACCENT Pooled Analysis of 12 Adjuvant Trials.
Romain CohenGilles ManceauJack FiskumGreg YothersRichard M GoldbergTakayuki YoshinoSteven R AlbertsCarmen AllegraAimery de GramontJean-Francois SeitzMichael O'ConnellDaniel HallerNorman WolmarkCharles ErlichmanAlberto ZaniboniSara LonardiRachel KerrAxel GrotheyFrank A SinicropeThierry AndréQian ShiPublished in: Journal of clinical oncology : official journal of the American Society of Clinical Oncology (2020)
Adding oxaliplatin to FP improves OS and DFS in patients with MSI stage III CC. Compared with MSS, MSI patients experienced better outcomes in the N1 group but similar survival in the N2 group.