Effect of Cuban Porcine Pulmonary Surfactant (Surfacen) and rCmPI-II Protease Inhibitor on Neutrophil Elastase Activity.

Yuliannis Lugones-Ladrón de Guevara Mercyleidi Díaz-Reyes Aymara Cabrera-Muñoz Arturo Chang-Monteagudo Maday Alonso Del Rivero Odalys Blanco-Hidalgo

Published in: MEDICC review (2022)

Surfacen and the rCmPI-II inhibitor have an anti-elastase effect on an activated neutrophil model. rCmPI-II does not affect Surfacen's interface property and, therefore, both can be evaluated for combined use in treating inflammatory lung diseases.

Keyphrases

pulmonary hypertension
oxidative stress