TRAF3 suppression encourages B cell recruitment and prolongs survival of microbiome-intact mice with ovarian cancer.

Jonathan ZoreaYair MotroRoei D MazorYifat Koren CarmiZiv ShulmanJamal MahajnaJacob Moran-GiladMoshe Elkabets

Published in: Journal of experimental & clinical cancer research : CR (2023)

TRAF3 is a tumor-derived immune-suppressive modulator that influences B-cell infiltration and activation, making it a potential target for enhancing anti-tumor B-cell responses in OC.

Keyphrases

high fat diet induced
free survival
human health
risk assessment
insulin resistance
climate change