Developmental Pharmacogenetics of SLCO2B1 on Montelukast Pharmacokinetics in Chinese Children.

Qian LiKai WangHai-Yan ShiYue-E WuYue ZhouMin KanYi ZhengGuo-Xiang HaoXin-Mei YangYi-Lei YangLe-Qun SuXiao-Ling WangEvelyne Jacqz-AigrainJun ZhouWei Zhao

Published in: Drug design, development and therapy (2019)

The developmental pharmacology of montelukast in Chinese children was evaluated. Weight and SLCO2B1 genotype were found to have independent significant impacts on the clearance of montelukast.

Keyphrases

young adults
physical activity
body mass index
weight loss
weight gain