Efficacy and safety of short-term use of a pelubiprofen CR and aceclofenac in patients with symptomatic knee osteoarthritis: A double-blinded, randomized, multicenter, active drug comparative, parallel-group, phase IV, non-inferiority clinical trial.

Joung Youp ShinMoon Jong ChangMyung Ku KimSeung-Baik KangKang-Il KimHee Gon ParkSahnghoon LeeSung-Hwan KimSeung-Beom HanHan Jun LeeYoung-Wan MoonJae-Doo Yoo

Published in: PloS one (2020)

Pelubiprofen CR 90 mg is as effective as aceclofenac 200 mg with reduced adverse events for the treatment of symptomatic knee osteoarthritis.

Keyphrases

knee osteoarthritis
double blind
clinical trial
open label
phase ii
placebo controlled
phase iii
study protocol
emergency department
adverse drug