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Patient-reported outcomes and neurotoxicity markers in patients treated with bispecific LV20.19 CAR T cell therapy.

Jennifer Mary KnightAniko SzaboIgli ArapiRuizhe WuAmanda EmmrichEdward HackettGarrett SauberSharon YimBryon JohnsonParameswaran N HariDina SchneiderBoro DropulicRachel N CusatisSteve W ColeCecilia J HillardNirav N Shah
Published in: Communications medicine (2022)
Elevated levels of kynurenine pathway metabolites among CAR T cell recipients are associated with depressed mood and neurotoxicity. Findings from this exploratory study are preliminary and warrant validation in a larger cohort.
Keyphrases
  • cell therapy
  • patient reported outcomes
  • stem cells
  • mesenchymal stem cells
  • bipolar disorder
  • ms ms
  • bone marrow
  • kidney transplantation