Antimicrobial resistance pattern and uropathogens distribution in children visiting a referral hospital in Mogadishu.
Abdikarin Ahmed MohamedYavuz BastugCem SenolMohamed Muktar KassimAbdisalam Abdullahi YusufAbdikarim Hussein MohamedPublished in: Future science OA (2024)
Aim: Studies concerning epidemiology and drug susceptibility patterns of pediatric urinary tract infection in developing countries are scarce. This study aimed to evaluate the antimicrobial resistance pattern and uropathogens distribution in children. Method: Four-year retrospective study included 840 participants in all pediatric age groups whose urine had been cultured. Results: The prevalence of culture-proven pediatric UTIs was 17.6% (148/840). Escherichia coli was the most common pathogen isolated from the cultures, accounting for (48%, 71/148), followed by Klebsiella pneumoniae (16.2%, 24/148). About 27% of the pathogens had a multidrug-resistant (MDR) pattern. A resistance rate against nitrofurantoin at 24.6%, fosfomycin at 15.2% and trimethoprim-sulfamethoxazole (SMX-TMP) at 79.7% was noted. Conclusion: E. coli and Klebsiella pneumoniae were the most common pathogens isolated.
Keyphrases
- antimicrobial resistance
- klebsiella pneumoniae
- multidrug resistant
- urinary tract infection
- escherichia coli
- gram negative
- drug resistant
- acinetobacter baumannii
- young adults
- risk factors
- primary care
- emergency department
- adverse drug
- healthcare
- biofilm formation
- candida albicans
- microbial community
- pseudomonas aeruginosa