Simultaneous determination of itraconazole and its CYP3A4-mediated metabolites including N-desalkyl itraconazole in human plasma using liquid chromatography-tandem mass spectrometry and its clinical application.
Yumi ImotoYasuaki MinoTakafumi NaitoTakaaki OnoJunichi KawakamiPublished in: Journal of pharmaceutical health care and sciences (2020)
This study developed a simultaneous determination method for concentrations of ITZ and its three metabolites including ND-ITZ in a clinical setting.