Effect of Periapical Diseases in Development of MRONJ in Immunocompromised Mouse Model.

Nian Jing RaoRu Qing YuJing Yi WangAlexandra HelmLi-Wu Zheng

Published in: BioMed research international (2019)

Apical periodontitis aggravates MRONJ under immunocompromised circumstances. Concurrent use of ZA and steroids inhibits alveolar bone resorption but increases the risk of developing MRONJ.

Keyphrases

mouse model
respiratory failure
bone loss
bone mineral density
locally advanced
soft tissue
radiation therapy
extracorporeal membrane oxygenation
mechanical ventilation
cone beam