Targeting KDM4C enhances CD8 + T cell mediated antitumor immunity by activating chemokine CXCL10 transcription in lung cancer.

Xiaohua JieYunshang ChenYe ZhaoXijie YangYingzhuo XuJian WangRui MengSheng ZhangXiaorong DongTao ZhangKunyu YangShuangbing XuGang Wu

Published in: Journal for immunotherapy of cancer (2022)

Our data reveal a crucial role for KDM4C in antitumor immunity in lung cancer and indicate that targeting KDM4C in combination with radioimmunotherapy might be a promising synergistic strategy in lung cancer.

Keyphrases

cancer therapy
electronic health record
drug delivery
single cell
gene expression
big data
artificial intelligence
data analysis