Prognostic Significance of a Scoring System Combining p16, Smoking, and Drinking Status in a Series of 131 Patients with Oropharyngeal Cancers.

Cyril BoulandDidier DequanterJérôme R LechienCharlotte HanssensNicolas De Saint AubainAntoine DigonnetRokneddine JavadianAntoine YanniAlexandra RodriguezIsabelle LoebFabrice JourneSven Saussez

Published in: International journal of otolaryngology (2021)

This study confirmed that the overexpression of the p16 protein could be viewed as a factor of good prognosis for RFS and OS of OSCC patients. The prognostic significance of a scoring system combining p16 expression, smoking, and drinking status was evaluated and concluded to be a more effective tool to determine therapeutic orientations based on the risk factors for better treatment relevance and survival.

Keyphrases

end stage renal disease
newly diagnosed
smoking cessation
prognostic factors
cell proliferation
binding protein
alcohol consumption
peritoneal dialysis
transcription factor
patient reported outcomes
small molecule