Assessment of Bone Marrow Involvement in B-Cell non-Hodgkin Lymphoma Using Immunoglobulin Gene Rearrangement Analysis with Next-Generation Sequencing.

Min Ji JeonEun Sang YuDae Sik KimChul Won ChoiHa Nui KimJung Ah KwonSoo-Young YoonJung Yoon

Published in: Journal of clinical laboratory analysis (2024)

NGS-based clonality analysis is an analytic platform with a substantial overall agreement with histopathological analysis. Assessment of both IGH and IGK genes for the clonal rearrangement analysis could be considered for the optimal diagnostic performance of BMI detection in B-cell NHL.

Keyphrases

bone marrow
mesenchymal stem cells
gene expression
body mass index
dna methylation
high throughput
transcription factor
weight loss
label free
data analysis
circulating tumor
genome wide analysis