Androgen receptor variant-driven prostate cancer II: advances in laboratory investigations.

Changxue LuLandon C BrownEmmanuel S AntonarakisAndrew J ArmstrongJun Luo

Published in: Prostate cancer and prostatic diseases (2020)

Current literature continues to support AR-Vs as biomarkers and therapeutic targets in prostate cancer. Laboratory investigations reveal both challenges and opportunities in targeting AR-Vs to overcome resistance to current AR-directed therapies.

Keyphrases

prostate cancer
radical prostatectomy
systematic review
genome wide
single cell
gene expression