A head-to-head comparison of two DREADD agonists for suppressing operant behavior in rats via VTA dopamine neuron inhibition.

Kate A Lawson Christina M Ruiz Stephen V Mahler

Published in: bioRxiv : the preprint server for biology (2023)

Findings demonstrate the usefulness of directly comparing DREADD agonists when optimizing behavioral chemogenetics, and highlight the importance of proper controls, regardless of the DREADD agonist employed.

Keyphrases

optic nerve
signaling pathway
uric acid