Carotid and Aortic Stiffness in Patients with Heterozygous Familial Hypercholesterolemia.

Alexandra Igorevna ErshovaAlexey N MeshkovTatyana A RozhkovaMaria V KalininaAlexander D DeevAnatoliy N RogozaTatyana V BalakhonovaSergey A Boytsov

Published in: PloS one (2016)

Our study demonstrated that treatment-naive patients with FH had stiffer carotid arteries than their relatives, but showed no difference in aortic stiffness. We also found out that the rate of reduction of elasticity of the aorta and carotid arteries in FH patients varies: it is observed earlier in carotid arteries than in the aorta.

Keyphrases

aortic valve
pulmonary artery
end stage renal disease
aortic dissection
ejection fraction
newly diagnosed
left ventricular
chronic kidney disease
blood flow
pulmonary hypertension
early onset
pulmonary arterial hypertension
replacement therapy