Interleukin 17A promotes cell migration, enhances anoikis resistance, and creates a microenvironment suitable for triple negative breast cancer tumor metastasis.

Yi-Fang TsaiChi-Cheng HuangYen-Shu LinChih-Yi HsuChing-Po HuangChun-Yu LiuJen-Hwey ChiuLing-Ming Tseng

Published in: Cancer immunology, immunotherapy : CII (2021)

We conclude that IL-17A promotes migratory and angiogenic activity in tumors, enhances anoikis resistance, and modulates the immune landscape of the tumor microenvironment such changes favor cancer metastasis.

Keyphrases

cell migration
papillary thyroid
stem cells
squamous cell
single cell
young adults
childhood cancer