Assessment of the predictive capability of modelling and simulation to determine bioequivalence of inhaled drugs: A systematic review.
Juliet RebelloBill BrashierSharvari R ShuklaPublished in: Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences (2022)
Overall, while there are different modelling techniques that have been used for inhaled drugs in asthma and COPD, there is very limited application of these models for assessment of bioequivalence of OIPs. This review also provides a ready reference of various parameters that have been considered in various models which will aid in evaluation if one model or hybrid in silico models need to be considered when assessing bioequivalence of OIPs.