The transcriptome of peripheral blood mononuclear cells in patients with clinical subtypes of late age-related macular degeneration.

Yousif SubhiMarie Krogh NielsenChristopher Rue MolbechCharlotte LiisborgHelle Bach SøndergaardFinn SellebjergTorben Lykke Sørensen

Published in: Immunity & ageing : I & A (2019)

We here map the global gene transcriptome of PBMCs related to clinical subtypes of late AMD and find evidence of subtype-specific immunological involvement. Our findings provide a transcriptomic insight into the systemic immunity associated with AMD.

Keyphrases

age related macular degeneration
single cell
rna seq
genome wide
copy number
drug induced
genome wide identification