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Discovery and biological evaluation of a potent small molecule CRM1 inhibitor for its selective ablation of extranodal NK/T cell lymphoma.

He LiuMeisuo LiuXibao TianHaina WangJiujiao GaoHanrui LiZhehuan ZhaoYu LiuCaigang LiuXuan ChenYongliang Yang
Published in: eLife (2023)
Funding: Yang's laboratory was supported by the National Natural Science Foundation of China (Grant: 81874301), the Fundamental Research Funds for Central University (Grant: DUT22YG122) and the Key Research project of 'be Recruited and be in Command' in Liaoning Province (Personal Target Discovery for Metabolic Diseases).
Keyphrases
  • small molecule
  • quality improvement
  • protein protein
  • south africa
  • public health
  • high throughput
  • nk cells
  • catheter ablation