Integrative Analysis of Germline Rare Variants in Clear and Non-Clear Cell Renal Cell Carcinoma.

Seunghun HanSabrina Y CampHoyin ChuRyan CollinsRiaz GillaniJihye ParkZiad BakounyCora A RickerBrendan ReardonNicholas MooreEric KofmanChris LabakiDavid BraunToni K ChoueiriSaud H AlDubayanEliezer M Van Allen

Published in: medRxiv : the preprint server for health sciences (2023)

in RCC requires careful adjustment for population stratification. In addition, previously underappreciated forms of germline variants may explain a portion of the missing heritability in RCC.

Keyphrases

copy number
renal cell carcinoma
dna repair
gene expression