Association of novel rare coding variants with juvenile idiopathic arthritis.

Xinyi MengXiaoyuan HouPing WangJoseph T GlessnerHui-Qi QuMichael E MarchSipeng ZhangXiaohui QiChonggui ZhuKenny NguyenXinyi GaoXiaoge LiYichuan LiuWentao ZhouShuyue ZhangJunyi LiYan SunJie YangPatrick M A SleimanQianghua XiaHakon HakonarsonJin Li

Published in: Annals of the rheumatic diseases (2021)

This study elucidated a novel landscape of recurrent rare coding variants in JIA patients and uncovered significant associations with JIA at the gene pathway level. The convergence of common variants and rare variants for autoimmune diseases is also highlighted in this study.

Keyphrases

juvenile idiopathic arthritis
copy number
end stage renal disease
chronic kidney disease
genome wide
disease activity
peritoneal dialysis
transcription factor
single cell