Serum osteopontin negatively impacts on intima-media thickness in patients with systemic lupus erythematosus.
Federico CarboneFranco DallegriFabrizio MontecuccoAlessandro PoggiFlavio Mariano NobiliFabio CacciapagliaAntonella AfeltraTiziano MoccettiBarbara M ColomboPublished in: European journal of clinical investigation (2019)
These results indicate that serum OPN levels were strongly associated with subclinical atherosclerosis in patients with LES and it might be a useful CV biomarker that requires additional validation in larger trials.